La indagación científica en la línea Neurociencia-Cognición-Aprendizaje, facilita encontrar relaciones entre factores que afectan la triada salud humana, aprendizaje y desempeño. A su vez, Aprendizaje y Felicidad, son know-how tan íntimamente ligados que al resultar alterados forman barreras que convergen en frustración de las personas, requiriendo un diagnóstico/manejo oportuno/apropiado para superarlas. Es el eje de trabajo al revisar artículos de la investigación científica en este blog.
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CORONAVIRUS COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU) ...
domingo, 29 de marzo de 2020
El cerebro tiene células madre capaces de generar neuronas después de nacer
Understanding the contribution of adult neural progenitor cells (NPCs) and their lineage potential is a great challenge in neuroscience. To reveal progenitor diversity and cell-lineage relationships of postnatal NPCs in the subventricular zone (SVZ), we performed in vivo lineage-tracing genetic analysis using the UbC-StarTrack. We determined the progeny of single SVZ-NPCs, the number of cells per clone, the dispersion of sibling cells, and the cell types within clones. Long-term analysis revealed that both the cell-dispersion pattern and number of cells comprising clones varied depending on the glial/neuronal nature of sibling cells. Sibling-olfactory interneurons were primarily located within the same layer, while sibling-glial cells populated SVZ-adjacent areas. Sibling astrocytes and interneurons did not form big clones, whereas oligodendroglial-lineage clones comprised the largest clones originated in adult brains. These results demonstrate the existence of SVZ postnatal bipotential progenitors that give rise to clones widely dispersed across the olfactory bulb and SVZ-adjacent areas.
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